136020-18-3

136020-18-3 structure
136020-18-3 structure
  • Name: 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine
  • Chemical Name: 4-amino-1-[(2R,5S,6R)-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]pyrimidin-2-one
  • CAS Number: 136020-18-3
  • Molecular Formula: C10H15N3O5
  • Molecular Weight: 257.24
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-06-04 07:59:56
  • Modify Date: 2024-02-01 15:06:56
  • 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name 4-amino-1-[(2R,5S,6R)-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]pyrimidin-2-one
Synonyms 2',3'-Dideoxy-hexopyranosyl cytidine
Description 1-(2,3-Dideoxy-β-D-erythro-hexo pyranosyl)cytosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.63g/cm3
Boiling Point 491.8ºC at 760mmHg
Molecular Formula C10H15N3O5
Molecular Weight 257.24
Flash Point 251.3ºC
Exact Mass 241.10600
PSA 111.59000
Vapour Pressure 9.77E-12mmHg at 25°C
Index of Refraction 1.691

~84%

136020-18-3 structure

136020-18-3

Literature: Boehringer, Markus; Roth, Hans-Joerg; Hunziker, Juerg; Goebel, Michael; Krishnan, Ravichandran; et al. Helvetica Chimica Acta, 1992 , vol. 75, # 5 p. 1416 - 1477

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136020-18-3 structure

136020-18-3

Literature: Boehringer, Markus; Roth, Hans-Joerg; Hunziker, Juerg; Goebel, Michael; Krishnan, Ravichandran; et al. Helvetica Chimica Acta, 1992 , vol. 75, # 5 p. 1416 - 1477