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kb-NB77-78

Names

[ CAS No. ]:
1350622-33-1

[ Name ]:
kb-NB77-78

[Synonym ]:
9-{[Dimethyl(2-methyl-2-propanyl)silyl]oxy}-1,2,3,4-tetrahydro-5H-chromeno[3,4-b]pyridin-5-one
5H-[1]Benzopyrano[3,4-b]pyridin-5-one, 9-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-1,2,3,4-tetrahydro-
9-(tert-butyldimethylsilyloxy)-3,4-dihydro-1h-chromeno[3,4-b]pyridin-5(2h)-one

Biological Activity

[Description]:

kb-NB77-78 is an analogue of CID797718, but shows no PKD inhibitory activity[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Cancer

[In Vitro]

kb-NB77-78 is an analogue of CID797718, but shows no PKD inhibitory activity.

[References]

[1]. George KM, et al. Design, Synthesis, and Biological Evaluation of PKD Inhibitors. Pharmaceutics. 2011;3(2):186-228.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
449.6±45.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H25NO3Si

[ Molecular Weight ]:
331.482

[ Flash Point ]:
225.7±28.7 °C

[ Exact Mass ]:
331.160370

[ PSA ]:
51.47000

[ LogP ]:
0.14

[ Appearance of Characters ]:
white solid

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.550

[ Storage condition ]:
-20℃

Related Compounds