Methyl ganoderate A acetonide

Names

[ CAS No. ]:
1346453-53-9

[ Name ]:
Methyl ganoderate A acetonide

Biological Activity

[Description]:

Methyl ganoderate A acetonide, a lanostane triterpene, is a natural product that could be isolated from the fruiting bodies of Ganoderma lucidum. Methyl ganoderate A acetonide is a potent AChE inhibitor with an IC50 value of 18.35 μM. Methyl ganoderate A acetonide can be used in research of Alzheimer’s disease (AD)[1].

[Related Catalog]:

Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> AChE

[Target]

AChE


[References]

[1]. Lee I, et, al. Selective cholinesterase inhibition by lanostane triterpenes from fruiting bodies of Ganoderma lucidum. Bioorg Med Chem Lett. 2011 Nov 1;21(21):6603-7.  

Chemical & Physical Properties

[ Molecular Formula ]:
C34H50O7

[ Molecular Weight ]:
570.76

Related Compounds

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