Octahydroaminoacridine succinate

Names

[ Name ]:
Octahydroaminoacridine succinate

[Synonym ]:
9-amino-1,2,3,4,5,6,7,8-octahydroacridine
9-Amino-1,2,3,4,5,6,7,8-octahydroacridin
Octahydroaminoacridine
9-Amino-sym.-octahydro-acridin
9-amino-1,2,3,4,5,6,7,8-octohydroacridine
Octohydroaminoacridine
1,2,3,4,5,6,7,8-octahydro-acridin-9-ylamine
UNII-2YM9179F4V

Biological Activity

[Description]:

Octahydroaminoacridine, a Tacrine analogue, is an acetylcholinesterse (AChE) and butyrylcholinesterase (BChE) inhibitor. Octahydroaminoacridine can be used for Alzheimer's disease (AD) research[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> AChE

[References]

[1]. Jiangbin Han, et al. Quantitation of the tacrine analogue octahydroaminoacridine in human plasma by liquid chromatography-tandem mass spectrometry. J Pharm Biomed Anal. 2009 Sep 8;50(2):171-4.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₈N₂

[ Molecular Weight ]:
202.30

[ Exact Mass ]:
202.14700

[ PSA ]:
39.64000

[ LogP ]:
2.35150

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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