Dimethyl 2-oxopentanedioate

Names

[ Name ]:
Dimethyl 2-oxopentanedioate

[Synonym ]:
MFCD00048052
2-Ketoglutaric Acid Dimethyl Ester
Dimethyl 2-Ketoglutarate
Dimethyl 2-oxopentanedioate
Glutaric acid, 2-oxo-, dimethyl ester
Pentanedioic acid, 2-oxo-, dimethyl ester
2-Oxoglutaric Acid Dimethyl Ester
DiMethyl 2-Oxoglutarate
Dimethyl2-oxoglutarate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
249.4±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₇H₁₀O₅

[ Molecular Weight ]:
174.151

[ Flash Point ]:
105.0±22.7 °C

[ Exact Mass ]:
174.052826

[ PSA ]:
69.67000

[ LogP ]:
-0.22

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.427

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2918300090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2918300090

[ Summary ]:
2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Articles

Deficiencies in Cellular Processes Modulated by the Retinoblastoma Protein Do Not Account for Reduced Human Cytomegalovirus Replication in Its Absence.

J. Virol. 89 , 11965-74, (2015)

Despite encoding multiple viral proteins that modulate the retinoblastoma (Rb) protein in a manner classically defined as inactivation, human cytomegalovirus (HCMV) requires the presence of the Rb pro...

Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition.

PLoS ONE 9(12) , e115144, (2014)

Recent work has highlighted glutaminase (GLS) as a key player in cancer cell metabolism, providing glutamine-derived carbon and nitrogen to pathways that support proliferation. There is significant in...

Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation.

Stem Cells 33 , 2613-27, (2015)

Autologous transplantation of cardiac progenitor cells (CPCs) alleviates myocardial dysfunction in the damaged heart; however, the mechanisms that contribute to their reparative qualities remain poorl...