NCS-382 (sodium salt)

Names

[ Name ]:
NCS-382 (sodium salt)

[Synonym ]:
5,7,8,9-Tetrahydro-5-hydroxy-6H-benzocyclohepten-6-ylidene acetic acid hydrate monosodium salt
NCS-382 HYDRATE
NCS-382,SODIUM SALT
6,7,8,9-TETRAHYDRO-5-HYDROXY-5H-BENZOCYCLOHEPT-6-YLIDENEACETIC ACID
NCS-382

Biological Activity

[Description]:

NCS-382 (sodium) is a potent GABA receptor antagonist. NCS-382 (sodium) has anti-sedative and anti-hypnotic activities and can be used in research related to neurological diseases[1].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[References]

[1]. Schmidt C, et al. Anti-sedative and anti-cataleptic properties of NCS-382, a gamma-hydroxybutyrate receptor antagonist. Eur J Pharmacol. 1991 Oct 22;203(3):393-7.

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
460.8ºC at 760mmHg

[ Melting Point ]:
141-143ºC

[ Molecular Formula ]:
C₁₃H₁₃NaO₃

[ Molecular Weight ]:
240.23

[ Flash Point ]:
246.6ºC

[ Exact Mass ]:
240.07600

[ PSA ]:
60.36000

[ LogP ]:
0.73260

[ Vapour Pressure ]:
2.74E-09mmHg at 25°C

Safety Information

[ Safety Phrases ]:
S22-S24/25

Related Compounds

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