GR103545

Names

[ Name ]:
GR103545

Biological Activity

[Description]:

GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). 11GR103545 is a radiotracer for imaging κ-OR in vivo[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Opioid Receptor

Signaling Pathways >> Neuronal Signaling >> Opioid Receptor

Research Areas >> Neurological Disease

[Target]

κ-opioid receptoro[1]

[References]

[1]. Hayes AG, et, al. A series of novel, highly potent and selective agonists for the kappa-opioid receptor. Br J Pharmacol. 1990 Dec;101(4):944-8.

[2]. Talbot PS, et, al. 11C-GR103545, a radiotracer for imaging kappa-opioid receptors in vivo with PET: synthesis and evaluation in baboons. J Nucl Med. 2005 Mar;46(3):484-94.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₉Cl₂N₃O₇

[ Molecular Weight ]:
530.40

Related Compounds

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