ACT-334441

Names

[ Name ]:
ACT-334441

[Synonym ]:
Y333RS1786
(2S)-3-{4-[5-(2-Cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy}-1,2-propanediol
1,2-Propanediol, 3-[4-[5-(2-cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-, (2S)-
MFCD30530772
cenerimod

Biological Activity

[Description]:

Cenerimod (ACT-334441) is a potent and orally available sphingosine 1-phosphate 1 receptor (S1P1) agonist extracted from patent WO 2016184939 A1 and WO 2011007324 A1, example 1, with an EC50 of 2.7 nM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> LPL Receptor

Research Areas >> Inflammation/Immunology

[Target]

EC50: 2.7 nM[2]

[References]

[1]. WO 2016184939 A1

[2]. WO 2011007324 A1

[Related Small Molecules]

Ki16425 | Siponimod | AM966 | Ozanimod | BMS-986020 | LPA2 antagonist 1 | TY-52156 | AM095 | Etrasimod | Ponesimod | Amiselimod hydrochloride | S1p receptor agonist 1 | ONO-7300243 | (S) FTY720 Phosphate

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
670.7±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₅H₃₁N₃O₅

[ Molecular Weight ]:
453.531

[ Flash Point ]:
359.4±34.3 °C

[ Exact Mass ]:
453.226379

[ LogP ]:
5.92

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.578

[ Storage condition ]:
2-8℃

Related Compounds

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