Levosulpiride-d3

Names

[ Name ]:
Levosulpiride-d3

[Synonym ]:
S-Sulpiride-d3
Levopraid-d3
Levosulpiride-d3
L-Sulpiride-d3
Sulpid-d3
Levopride-d3
Levobren-d3
(-)-N-[(1-Ethyl-2-pyrrolidinyl)methyl]-5-sulfamoyl-o-anisamide-d3
(-)-Sulpiride-d3

Biological Activity

[Description]:

Levosulpiride-d3 (RV-12309-d3) is the deuterium labeled Levosulpiride. Levosulpiride (RV-12309) is the (S)-enantiomer of sulpiride, which is a D2 receptor a antagonist, an atypical antipsychotic drug of the benzamide class[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

[2]. Triebel J, et al. From Bench to Bedside: Translating the Prolactin/Vasoinhibin Axis. Front Endocrinol (Lausanne). 2017;8:342. Published 2017 Dec 11.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₅H₂₀D₃N₃O₄S

[ Molecular Weight ]:
344.44400

[ Exact Mass ]:
344.16000

[ PSA ]:
113.60000

[ LogP ]:
2.85050

Related Compounds

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