<Suppliers Price>

CGP 36216

Names

[ CAS No. ]:
123691-29-2

[ Name ]:
CGP 36216

Biological Activity

[Description]:

CGP36216 (Compound 9) is a GABAB receptor antagonist. CGP36216 binds to GABAB receptor with a Ki value of 0.3 μM. CGP36216 can be used for research of anxiety and trauma-related disorders[1][2].

[Related Catalog]:

Signaling Pathways >> Membrane Transporter/Ion Channel >> GABA Receptor
Research Areas >> Neurological Disease
Signaling Pathways >> Neuronal Signaling >> GABA Receptor

[Target]

GABAB receptor[1]


[References]

[1]. William Howson, et al. Biological activity of 3-aminopropyl (methyl) phosphinic acid, a potent and selective GABAB agonist with CNS activity. Bioorganic & Medicinal Chemistry Letters. Volume 3, Issue 4, April 1993, Pages 515-518.

[2]. Adkins JM, et al. Presynaptic GABAB receptor inhibition sex dependently enhances fear extinction and attenuates fear renewal. Psychopharmacology (Berl). 2021 Aug;238(8):2059-2071.  

Chemical & Physical Properties

[ Molecular Formula ]:
C5H14NO2P

[ Molecular Weight ]:
151.14

[ Exact Mass ]:
187.05300

[ PSA ]:
73.13000

[ LogP ]:
2.12780

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.