Topoisomerase I inhibitor 9

Names

[ Name ]:
Topoisomerase I inhibitor 9

Biological Activity

[Description]:

Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

Research Areas >> Infection

[Target]

34.81 μM[1]

[References]

[1]. Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₁₅Br₂FN₂

[ Molecular Weight ]:
498.19

Related Compounds

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