1228150-86-4

1228150-86-4 structure

Name: Topoisomerase I inhibitor 9
Chemical Name: Topoisomerase I inhibitor 9
CAS Number: 1228150-86-4
Molecular Formula: C₂₃H₁₅Br₂FN₂
Molecular Weight: 498.19
Catalog: Signaling Pathways Cell Cycle/DNA Damage Topoisomerase
Create Date: 2023-12-26 11:49:26
Modify Date: 2024-01-29 10:37:17
Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].

Name	Topoisomerase I inhibitor 9

Description	Topoisomerase I inhibitor 9 (compound 3d) is a leishmanial topoisomerase IB inhibitor. Topoisomerase I inhibitor 9 has antileishmanial activity against L. donovani promastigotes, with the IC50 of 34.81μM[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase Research Areas >> Infection
Target	34.81 μM[1]
References	[1]. Kour P, et al. Design, synthesis, and biological evaluation of 3,3'-diindolylmethane N-linked glycoconjugate as a leishmanial topoisomerase IB inhibitor with reduced cytotoxicity. RSC Med Chem. 2023;14(10):2100-2114. Published 2023 Aug 30.

Molecular Formula	C₂₃H₁₅Br₂FN₂
Molecular Weight	498.19