4'-Bromo-resveratrol

Names

[ Name ]:
4'-Bromo-resveratrol

[Synonym ]:
4-Bromo-Resveratrol

Biological Activity

[Description]:

4'-Bromo-resveratrol is a potent and dual inhibitor Sirtuin-1 and Sirtuin-3. 4'-Bromo-resveratrol inhibits melanoma cell growth through mitochondrial metabolic reprogramming. 4'-Bromo-resveratrol imparts antiproliferative effects in melanoma cells through a metabolic reprogramming and affecting the cell cycle and apoptosis signaling[1].

[Related Catalog]:

Signaling Pathways >> Epigenetics >> Sirtuin

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Sirtuin

[References]

[1]. George J, et al. 4'-Bromo-resveratrol, a dual Sirtuin-1 and Sirtuin-3 inhibitor, inhibits melanoma cell growth through mitochondrial metabolic reprogramming. Mol Carcinog. 2019;58(10):1876-1885.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₁BrO₂

[ Molecular Weight ]:
291.14000

[ Exact Mass ]:
289.99400

[ PSA ]:
40.46000

[ LogP ]:
4.03070

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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