Quetiapine D4 hemifumarate

Names

[ Name ]:
Quetiapine D4 hemifumarate

[Synonym ]:
[2H4]-Quetiapine hemifumarate

Biological Activity

[Description]:

Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine hemifumarate is a 5-HT receptors agonist and a dopamine receptor antagonist. Antidepressant and anxiolytic effects[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Cross AJ, et al. Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models. Br J Pharmacol. 2016 Jan;173(1):155-66.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₃D₄N₃O₄S

[ Molecular Weight ]:
503.60400

[ Exact Mass ]:
503.20300

[ PSA ]:
148.20000

[ LogP ]:
1.87920

Related Compounds

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