5-Benzyloxyindole
Names
[ CAS No. ]:
1215-59-4
[ Name ]:
5-Benzyloxyindole
[Synonym ]:
5-Benzyloxyindole
1H-Indole, 5- (phenylmethoxy)-
5-(Benzyloxy)indole
1H-Indole, 5-(phenylmethoxy)-
5-Benzyindole
Indole, 5- (benzyloxy)-
5-benzyloxy-indol
Benzyloxy-5 indole
5-phenylmethoxyindole
bredreck's
EINECS 214-930-1
5-(Benzyloxy)-1H-indole
5-phenylmethoxy-1H-indole
5-BnO-indole
5-BENZYLOXY-1H-INDOLE
MFCD00005676
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
411.6±20.0 °C at 760 mmHg
[ Melting Point ]:
100-104 °C(lit.)
[ Molecular Formula ]:
C15H13NO
[ Molecular Weight ]:
223.270
[ Flash Point ]:
148.9±12.0 °C
[ Exact Mass ]:
223.099716
[ PSA ]:
25.02000
[ LogP ]:
3.71
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.670
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
ethanol: may be hazy yellow
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NL4850000
- CHEMICAL NAME :
- Indole, 5-benzyloxy-
- CAS REGISTRY NUMBER :
- 1215-59-4
- BEILSTEIN REFERENCE NO. :
- 0173532
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H13-N-O
- MOLECULAR WEIGHT :
- 223.29
- WISWESSER LINE NOTATION :
- T56 BMJ GO1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 9,453,1974
Safety Information
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S24/25-S22
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
NL4850000
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Bioorg. Med. Chem. Lett. 20 , 7076-9, (2010)
5-Benzyloxytryptamine 19 was found to act as an antagonist of the TRPM8 ion-channel. For example, 19 had an IC(50) of 0.34 μM when menthol was used as the stimulating agonist. Related commercially-ava...