HA 01-0196

Names

[ Name ]:
HA 01-0196

[Synonym ]:
Fenitrothion metabolite
5-Hydroxy-2-nitrotoluene
Phenol,3-methyl-4-nitro
Phenol, 3-methyl-4-nitro-
4-nitro-3-methyl-phenol
HA 01-0196
2-Nitro-5-hydroxytoluene
4-Nitro-m-cresol,5-Hydroxy-2-nitrotoluene
3-Methyl-4-nitrophenol
4-Nitro-5-methylphenol
EINECS 219-952-5
4-Nitro-3-cresol
P-NITRO-M-CRESOL
4-Nitro-m-cresol
3-Me-4-NO2 phenol
m-Cresol,4-nitro
3-hydroxy-6-nitro-toluene
4-Nitro-3-methylphenol,
3-Methyl-4-nitrobenzolol
MFCD00007333

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
304.9±30.0 °C at 760 mmHg

[ Melting Point ]:
125-130 °C(lit.)

[ Molecular Formula ]:
C₇H₇NO₃

[ Molecular Weight ]:
153.135

[ Flash Point ]:
140.0±13.0 °C

[ Exact Mass ]:
153.042587

[ PSA ]:
66.05000

[ LogP ]:
2.03

[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C

[ Index of Refraction ]:
1.597

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GP2625000

CHEMICAL NAME :: m-Cresol, 4-nitro-

CAS REGISTRY NUMBER :: 2581-34-2

BEILSTEIN REFERENCE NO. :: 1868105

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C7-H7-N-O3

MOLECULAR WEIGHT :: 153.15

WISWESSER LINE NOTATION :: WNR DQ B1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 90 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intracerebral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 15 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg/10W (Intermittent)

REFERENCE :: EESADV Ecotoxicology and Environmental Safety. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1977- Volume(issue)/page/year: 9,47,1985

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R36/37/38

[ Safety Phrases ]:
S26-S36/37-S37/39

[ RIDADR ]:
UN 2446 6.1/PG 3

[ WGK Germany ]:
3

[ RTECS ]:
GP2625000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
29089000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2908999090

[ Summary ]:
2908999090 halogenated, sulphonated, nitrated or nitrosated derivatives of phenols or phenol-alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Improvement of an efficient separation method for chemicals in diesel exhaust particles: analysis for nitrophenols.

Environ. Sci. Pollut. Res. Int. 15(4) , 318-21, (2008)

Diesel exhaust is believed to consist of thousands of organic constituents and is a major cause of urban pollution. We recently reported that a systematic separation procedure involving successive sol...

Measurement of nitrophenols in rain and air by two-dimensional liquid chromatography-chemically active liquid core waveguide spectrometry.

Anal. Chem. 82(13) , 5838-43, (2010)

We report a novel system to analyze atmospheric nitrophenols (NPs). Rain or air sample extracts (1 mL) are preconcentrated on a narrow bore (2 mm) aliphatic anion exchanger. In the absence of strong r...

New analytical method for sensitive quantification of urinary 3-methyl-4-nitrophenol to assess fenitrothion exposure in general population and occupational sprayers.

Toxicol. Lett. 210(2) , 220-4, (2012)

The measurement of blood cholinesterase (ChE) activities is adopted worldwide for biological monitoring of exposure to organophosphorus insecticides (OPs). Recent development of analytical chemistry h...