8-Bromo-9-(β-D-xylofuranosyl) guanine

Names

[ CAS No. ]:
1212650-12-8

[ Name ]:
8-Bromo-9-(β-D-xylofuranosyl) guanine

Biological Activity

[Description]:

8-Bromo-9-(β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C10H12BrN5O5

[ Molecular Weight ]:
362.14

Related Compounds

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