3-Nitrochlorobenzene
Names
[ CAS No. ]:
121-73-3
[ Name ]:
3-Nitrochlorobenzene
[Synonym ]:
1-Chloro-3-nitrobenzene
1-Nitro-3-chlorobenzene
1-Chloro-3-nitro-benzene
3-Chloro-1-nitrobenzene
Benzene, 1-chloro-3-nitro-
m-nitrochlorobenzene
3-Chloronitrobenzene
3-nitrophenyl chloride
3-Nitrochlorobenzene
m-chloronitrobenzene
EINECS 204-496-1
MFCD00007202
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
236.0±0.0 °C at 760 mmHg
[ Melting Point ]:
43-47 °C(lit.)
[ Molecular Formula ]:
C6H4ClNO2
[ Molecular Weight ]:
157.555
[ Flash Point ]:
103.3±0.0 °C
[ Exact Mass ]:
156.993057
[ PSA ]:
45.82000
[ LogP ]:
2.64
[ Vapour Pressure ]:
0.1±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.580
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong acids, strong reducing agents.
[ Water Solubility ]:
INSOLUBLE
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ0940000
- CHEMICAL NAME :
- Benzene, 1-chloro-3-nitro-
- CAS REGISTRY NUMBER :
- 121-73-3
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H4-Cl-N-O2
- MOLECULAR WEIGHT :
- 157.56
- WISWESSER LINE NOTATION :
- WNR CG
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 420 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,92,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 25(8),50,1981 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 80 ug/m3/24H/73D-C
- TOXIC EFFECTS :
- Behavioral - muscle contraction or spasticity
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 35(4),44,1970 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 65,263,1996 IARC Cancer Review:Human Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 65,263,1996 IARC Cancer Review:Group 3 IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 65,263,1996 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-POLAND:TWA 1 mg/m3 JAN 1993 OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H400
[ Precautionary Statements ]:
P273
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
T:Toxic;
[ Risk Phrases ]:
R23/24/25
[ Safety Phrases ]:
S22-S24/25-S60-S61-S45-S38-S36/37/39-S28A
[ RIDADR ]:
UN 1578 6.1/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
CZ0940000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
29049085
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2904901200
[ Summary ]:
2904901200 1-chloro-3-nitrobenzene。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%
Articles
Nat. Protoc. 5(3) , 429-38, (2010)
This protocol describes the aerobic oxidation of aromatic anilines to aromatic azo compounds using gold (Au) nanoparticles supported on TiO(2) as a catalyst. Yields above 98% are achieved under a few ...
2-Chloronitrobenzene, 3-chloronitrobenzene and 4-chloronitrobenzene.IARC Monogr. Eval. Carcinog. Risks Hum. 65 , 263-96, (1996)
[Hygienic study of the stability of methylnitrophos and pentachloronitrobenzene used in agriculture].
Gig. Sanit. (2) , 74-5, (1983)