BI 653048

Names

[ CAS No. ]:
1198784-72-3

[ Name ]:
BI 653048

Biological Activity

[Description]:

BI 653048 is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with anti-inflammatory effects[1]. BI 653048, compound 103 extracted from patent WO2005028501A1, is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus[2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Metabolic Enzyme/Protease >> HCV Protease

Signaling Pathways >> GPCR/G Protein >> Glucocorticoid Receptor

[Target]

IC50: Glucocorticoid (GC)[1]

[References]

[1]. Reeves JT, et al. Development of a large scale asymmetric synthesis of the glucocorticoid agonist BI 653048 BS H3PO4.J Org Chem. 2013 Apr 19;78(8):3616-35.

[2]. Montse Llinas-Brunet, et al. Latest bibliographic data on file with the International Bureau

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₂₅F₄N₃O₄S

[ Molecular Weight ]:
515.52

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.