(4-Aminophenyl)acetic acid
Names
[ CAS No. ]:
1197-55-3
[ Name ]:
(4-Aminophenyl)acetic acid
[Synonym ]:
UNII:1IED47A544
(4-AMINO-PHENYL)-ACETIC ACID
4-aminophenyl-acetic acid
4-Aminobenzeneacetic acid
p-Aminophenylacetic Acid
4-(AMINOPHENYL)ACETIC ACID
2-(4-aminophenyl)acetic acid
(4-AMINOPHENYL)ACETICACID
Phenylglycine base
MFCD00007916
4-AMINOPHENYLACETIC ACID FOR SYNTHESIS
(4-AMINOPHENYL)ACETIC ACID
EINECS 214-828-7
4-Aminophenylacetic acid
H-4-APH-OH
4-Carboxymethylaniline
RARECHEM AL BO 0220
Benzeneacetic acid, 4-amino-
BENZENEACETICACID, 4-AMINO-
4-Aminophenylacetic
DL-Phenylglycine
(para-Aminophenyl)acetic acid
Desacetyl Actarit
4-AMino acid
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
344.0±17.0 °C at 760 mmHg
[ Melting Point ]:
201 °C (dec.)(lit.)
[ Molecular Formula ]:
C8H9NO2
[ Molecular Weight ]:
151.163
[ Flash Point ]:
161.9±20.9 °C
[ Exact Mass ]:
151.063324
[ PSA ]:
63.32000
[ LogP ]:
0.22
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.615
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AF3550000
- CHEMICAL NAME :
- Acetic acid, (p-aminophenyl)-
- CAS REGISTRY NUMBER :
- 1197-55-3
- BEILSTEIN REFERENCE NO. :
- 2208094
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H9-N-O2
- MOLECULAR WEIGHT :
- 151.18
- WISWESSER LINE NOTATION :
- ZR D1VQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 2500 ug/plate
- REFERENCE :
- DEMAEP Dental Materials. (Munksgaard International Pub., POB 2148, DK-1016 Copenhagen K, Denmark) V.1- 1985- Volume(issue)/page/year: 2,163,1986
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S22-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
AF3550000
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2922499990
[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%
Articles
J. Physiol. 512 ( Pt 3) , 629-34, (1998)
1. 4-Aminomethylbenzoic acid, a molecule which mimics the special configuration of a dipeptide, competitively inhibits peptide influx in both Xenopus Laevis oocytes expressing rabbit PepT1 and through...
Preparation of 4-aminophenylacetic acid derivatives with promising antimicrobial activity.Acta. Pharm. 56(3) , 273-84, (2006)
Condensation of 4-aminophenylacetic acid with phthalic anhydride gave (dioxoisoindolin-2-yl)phenylacetic acid (1), which was employed as the key intermediate in the synthesis of title compounds 2-8. T...
Peptide mimics as substrates for the intestinal peptide transporter.J. Biol. Chem. 273(1) , 20-2, (1998)
4-Aminophenylacetic acid (4-APAA), a peptide mimic lacking a peptide bond, has been shown to interact with a proton-coupled oligopeptide transporter using a number of different experimental approaches...