Alosetron D3

Names

[ CAS No. ]:
1190043-13-0

[ Name ]:
Alosetron D3

[Synonym ]:
1H-Pyrido[4,3-b]indol-1-one, 2,3,4,5-tetrahydro-5-(methyl-d3)-2-[(4-methyl-1H-imidazol-5-yl)methyl]-
5-(2H3)Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one

Biological Activity

[Description]:

Alosetron D3 (GR 68755 D3) is a deuterium labeled Alosetron. Alosetron is a serotonin 5HT3-receptor antagonist[1].

[Related Catalog]:

Research Areas >> Neurological Disease

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[References]

[1]. Harris LA, et al. Alosetron: an effective treatment for diarrhea-predominant irritable bowel syndrome. Womens Health (Lond). 2007 Jan;3(1):15-27.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
648.1±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₅D₃N₄O

[ Molecular Weight ]:
297.370

[ Flash Point ]:
345.8±31.5 °C

[ Exact Mass ]:
297.166901

[ LogP ]:
0.88

[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C

[ Index of Refraction ]:
1.707

Related Compounds

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