<Suppliers Price>

AN3199

Names

[ CAS No. ]:
1187187-10-5

[ Name ]:
AN3199

[Synonym ]:
Butyl 6-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]nicotinate
3-Pyridinecarboxylic acid, 6-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-, butyl ester

Biological Activity

[Description]:

AN3199 is a PDE4 inhibitor with IC50 of 94.5 nM.IC50 value: 94.5 nM [1]Target: PDE4The detailed information please refer to Compound 11 in the reference.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE)
Research Areas >> Inflammation/Immunology

[References]

[1]. Zhang YK, et al. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2270-4.

[2]. Akama Tsutomu, et al. Preparation of boron-containing small molecules as anti-inflammatory agents. From PCT Int. Appl. (2009), WO 2009111676 A2 20090911.


[Related Small Molecules]

3-Isobutyl-1-methylxanthine | rolipram | PF-04957325 | AN-2728 | GLPG1690 | BAY-60-7550 | Icariin | Ibudilast | PF-8380 | TAK-063 | Dipyridamole | Cilostazol | GSK256066 | Cialis | Pentoxifylline

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
468.7±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C17H18BNO5

[ Molecular Weight ]:
327.139

[ Flash Point ]:
237.3±31.5 °C

[ Exact Mass ]:
327.127808

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.581

[ Storage condition ]:
2-8℃

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.