1187187-10-5

1187187-10-5 structure

Name: AN3199
Chemical Name: AN3199
CAS Number: 1187187-10-5
Molecular Formula: C₁₇H₁₈BNO₅
Molecular Weight: 327.139
Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
Create Date: 2018-04-29 14:41:25
Modify Date: 2025-08-25 19:36:15
AN3199 is a PDE4 inhibitor with IC50 of 94.5 nM.IC50 value: 94.5 nM [1]Target: PDE4The detailed information please refer to Compound 11 in the reference.

Name	AN3199
Synonyms	Butyl 6-[(1-hydroxy-1,3-dihydro-2,1-benzoxaborol-5-yl)oxy]nicotinate 3-Pyridinecarboxylic acid, 6-[(1,3-dihydro-1-hydroxy-2,1-benzoxaborol-5-yl)oxy]-, butyl ester

Description	AN3199 is a PDE4 inhibitor with IC50 of 94.5 nM.IC50 value: 94.5 nM [1]Target: PDE4The detailed information please refer to Compound 11 in the reference.
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Phosphodiesterase (PDE) Research Areas >> Inflammation/Immunology
References	[1]. Zhang YK, et al. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2270-4. [2]. Akama Tsutomu, et al. Preparation of boron-containing small molecules as anti-inflammatory agents. From PCT Int. Appl. (2009), WO 2009111676 A2 20090911.