ICI 192605
Names
[ CAS No. ]:
117621-64-4
[ Name ]:
ICI 192605
[Synonym ]:
6-(2-(2-Chlorophenyl-4-hydroxyphenyl)-1,3-dioxan-5-yl)hexenoic acid
4(Z)-6-(2-o-chlorophenyl-4-o-hydroxyphenyl-1,3-dioxan-cis-5-yl) hexenoic acid
4-Hexenoic acid,6-(2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl)-,(2alpha,4alpha,5alpha(Z))
(4Z)-rel
4(Z)-6-(2,4,5-cis)-[(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl]hexenoic acid
(Z)-6-(-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl)hex-4-enoic acid
(4Z)-6-<(2RS,4RS,5SR)-2-(2-chlorophenyl)-4-(2-hydroxyphenyl)-1,3-dioxan-5-yl>hex-4-enoic acid
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.262 g/cm3
[ Boiling Point ]:
540.1ºC at 760 mmHg
[ Molecular Formula ]:
C22H23ClO5
[ Molecular Weight ]:
402.86800
[ Flash Point ]:
280.4ºC
[ Exact Mass ]:
402.12300
[ PSA ]:
75.99000
[ LogP ]:
5.25960
[ Vapour Pressure ]:
1.7E-12mmHg at 25°C
[ Index of Refraction ]:
1.583
Safety Information
[ Symbol ]:
GHS07, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H410
[ Precautionary Statements ]:
P273-P501
[ RIDADR ]:
UN 3077 9 / PGIII
Articles
Placenta 32(12) , 941-8, (2011)
As the placenta is devoid of autonomic innervation, umbilical-placental vascular tone should be under the control of tissue and humoral factors. Among the numerous stimuli capable of challenging the p...
Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle.Clin. Exp. Allergy 39(2) , 236-45, (2009)
Isoprostanes are prostaglandin (PG)-like compounds synthesized by oxidative stress, not by cyclooxygenase, and increase in bronchoalveolar lavage fluid of patients with asthma. The airway inflammation...
Endothelial thromboxane production plays a role in the contraction caused by 5-hydroxytryptamine in rat basilar arteries.Eur. J. Pharmacol. 243(2) , 193-9, (1993)
The goal of the present study was to characterize the role of the endothelium in the 5-hydroxytryptamine (5-HT)-induced contraction of the rat basilar artery. Rat basilar artery segments were mounted ...