(Z)-Pitavastatin calcium

Names

[ Name ]:
(Z)-Pitavastatin calcium

[Synonym ]:
Pitavastatin Impurity 5

Biological Activity

[Description]:

(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent hydroxymethylglutaryl-CoA (HMG-CoA) reductase inhibitor. Pitavastatin calcium inhibits cholesterol synthesis from acetic acid with an IC50 of 5.8 nM in HepG2 cells[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Kajinami K, et al. Pitavastatin: efficacy and safety profiles of a novel synthetic HMG-CoA reductase inhibitor.Cardiovasc Drug Rev. 2003 Fall;21(3):199-215.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₅H₂₄FNO_4.1/₂Ca

[ Molecular Weight ]:
420.4528232

Related Compounds

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