CL-275838

Names

[ CAS No. ]:
115931-65-2

[ Name ]:
CL-275838

[Synonym ]:
CL-275838

Biological Activity

[Description]:

CL-275838 is a memory-enhancing agent, also with potent antidepressant activities.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Neurological Disease

[In Vivo]

CL 275,838 metabolism has sex-dependent differences in rat. CL 275,838 does not appreciably affect its own oxidation or cause significant hepatic microsomal enzyme induction in the male or female rat, except for slight enhancement of some components of the P450 system at doses (300 mg/kg once daily for 7 days) well above the effective pharmacological range[1].

[References]

[1]. Ferrarese A, et al. Hepatic microsomal metabolism of the potential memory-enhancing agent, CL 275,838, to its desbenzyl derivative. Xenobiotica. 1993 Sep;23(9):1007-16.


[Related Small Molecules]

Captisol | Cyclosporin A | H2DCFDA | 0MPTP hydrochloride | GW4869 | Etomoxir | TD139 | Mitoquinone mesylate | GSK2795039 | JC-1 | BAPTA-AM | AP 20187 | Setanaxib (GKT137831) | D-Luciferin | Crotaline

Chemical & Physical Properties

[ Density]:
1.33g/cm3

[ Boiling Point ]:
636.7ºC at 760mmHg

[ Molecular Formula ]:
C27H25F3N6O

[ Molecular Weight ]:
506.52200

[ Flash Point ]:
338.9ºC

[ Exact Mass ]:
506.20400

[ PSA ]:
68.40000

[ LogP ]:
3.76798

[ Vapour Pressure ]:
4.11E-16mmHg at 25°C

[ Index of Refraction ]:
1.634

[ Storage condition ]:
2-8℃

Related Compounds