2-Amino-2-methyl-1,3-propanediol

Names

[ CAS No. ]:
115-69-5

[ Name ]:
2-Amino-2-methyl-1,3-propanediol

[Synonym ]:
AMPD,Ammediol
1,3-Propanediol, 2-amino-2-methyl-
2-amino-2-methylpropane-1,3-diol
2-Amino-2-methyl-1,3-propanediol
EINECS 204-100-7
MFCD00004678

Biological Activity

[Description]:

2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change materials (PCMs). Amino-2-methyl-1,3-propanediol can be used to make surfactants, vulcanization accelerators and as a biological buffer[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. RyoheiGotoh, et al. Controlling heat release of crystallization from supercooling state of a solid-solid PCM, 2-amino-2-methyl-1,3-propanediol. International Journal of Heat and Mass Transfer, 2019, 1132-1140.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
271.5±0.0 °C at 760 mmHg

[ Melting Point ]:
100-110 °C(lit.)

[ Molecular Formula ]:
C₄H₁₁NO₂

[ Molecular Weight ]:
105.136

[ Flash Point ]:
109.7±21.8 °C

[ Exact Mass ]:
105.078979

[ PSA ]:
66.48000

[ LogP ]:
-1.16

[ Vapour density ]:
3.63 (vs air)

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.494

[ Stability ]:
Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids.

[ Water Solubility ]:
2500 g/L (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY2975000

CHEMICAL NAME :: 1,3-Propanediol, 2-amino-2-methyl-

CAS REGISTRY NUMBER :: 115-69-5

BEILSTEIN REFERENCE NO. :: 0635708

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C4-H11-N-O2

MOLECULAR WEIGHT :: 105.16

WISWESSER LINE NOTATION :: Q1XZ1&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - coma

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 22,315,1940 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82132 No. of Facilities: 38 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 66 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82132 No. of Facilities: 663 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 7513 (estimated) No. of Female Employees: 5523 (estimated)

Safety Information

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H290-H315-H319-H335

[ Precautionary Statements ]:
P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
UN 3259 8/PG 2

[ WGK Germany ]:
1

[ RTECS ]:
TY2975000

[ Hazard Class ]:
8.0

[ HS Code ]:
29221980

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 29221980

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