2-(Hydroxymethyl)-2-nitropropan-1,3-diol
Names
[ CAS No. ]:
126-11-4
[ Name ]:
2-(Hydroxymethyl)-2-nitropropan-1,3-diol
[Synonym ]:
Trimethylolnitromethane
2-Hydroxymethyl-2-nitro-1,3-propanediol
1,3-Propanediol, 2-(hydroxymethyl)-2-nitro-
2-(Hydroxymethyl)-2-nitro-1,3-propanediol
TRIHYDROXYMETHYLNITROMETHANE
EINECS 204-769-5
2-HYDROXYMETHYL-2-NITRO-PROPANE-1,3-DIOL
2-(hydroxymethyl)-2-nitropropane-1,3-diol
TRIS (HYDROXY METHYL) NITROMETHANE
1,3-Propanediol, 2- (hydroxymethyl)-2-nitro-
2-(Hydroxymethyl)-2-nitropropan-1,3-diol
TRIS(HYDROXYMETHYL) NITROMETHANE
MFCD00007395
tris(Hydroxymethyl)nitromethane (Tris Nitro)
Tris(hydroxymethyl)nitromethan
Chemical & Physical Properties
[ Density]:
1.5±0.1 g/cm3
[ Boiling Point ]:
445.6±45.0 °C at 760 mmHg
[ Melting Point ]:
160 °C (dec.)(lit.)
[ Molecular Formula ]:
C4H9NO5
[ Molecular Weight ]:
151.118
[ Flash Point ]:
209.3±17.2 °C
[ Exact Mass ]:
151.048065
[ PSA ]:
106.51000
[ LogP ]:
0.35
[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C
[ Index of Refraction ]:
1.536
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TY7350000
- CHEMICAL NAME :
- 1,3-Propanediol, 2-(hydroxymethyl)-2-nitro-
- CAS REGISTRY NUMBER :
- 126-11-4
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C4-H9-N-O5
- MOLECULAR WEIGHT :
- 151.14
- WISWESSER LINE NOTATION :
- WNX1Q1Q1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IMSUAI Industrial Medicine and Surgery. (Northbrook, IL) V.18-42, 1949-73. For publisher information, see IOHSA5. Volume(issue)/page/year: 39,56,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCOC** Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. (Topeka, KS) Volume(issue)/page/year: -,1198,1966
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 4 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- KHFZAN Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1967- Volume(issue)/page/year: 11(1),73,1977
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation
- REFERENCE :
- JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 22,315,1940 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M3866 No. of Facilities: 237 (estimated) No. of Industries: 6 No. of Occupations: 13 No. of Employees: 4196 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M3866 No. of Facilities: 709 (estimated) No. of Industries: 16 No. of Occupations: 20 No. of Employees: 20046 (estimated) No. of Female Employees: 609 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
TY7350000
[ HS Code ]:
2905590090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2905590090
[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
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Arch. Dermatol. 118(12) , 997-1002, (1982)
Two machinists were seen whose chronic hand dermatitis was explained by allergic sensitivity to a biocide, Tris Nitro (2-[hydroxymethyl]-2-nitro-1,3-propanediol), which was added to their metalworking...