7-TFA-ap-7-Deaza-ddA

Names

[ Name ]:
7-TFA-ap-7-Deaza-ddA

[Synonym ]:
N-(3-{4-Amino-7-[(2R,5S)-5-(hydroxymethyl)tetrahydro-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-propyn-1-yl)-2,2,2-trifluoroacetamide
Acetamide, N-[3-[4-amino-7-[(2R,5S)-tetrahydro-5-(hydroxymethyl)-2-furanyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl]-2-propyn-1-yl]-2,2,2-trifluoro-

Biological Activity

[Description]:

7-TFA-ap-7-Deaza-ddA (compound 19c, US20060281100A1), a nucleotide derivative, can be used in the synthesis of thiotriphosphate nucleotide dye terminators which can be used in DNA sequencing reactions[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Shen G, et, al. Thiotriphosphate nucleotide dye terminators. US20060281100A1.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
650.9±55.0 °C at 760 mmHg

[ Melting Point ]:
167-169 °C(Solv: ethyl ether (60-29-7))

[ Molecular Formula ]:
C₁₆H₁₆F₃N₅O₃

[ Molecular Weight ]:
383.325

[ Flash Point ]:
347.4±31.5 °C

[ Exact Mass ]:
383.120514

[ LogP ]:
1.46

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.639

[ Storage condition ]:
2-8℃

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.