5-Iodocytidine

Names

[ Name ]:
5-Iodocytidine

[Synonym ]:
5-Iodo-D-cytidine
5-iodo-cytidine
iodocytidine
1-D-Ribofuranosyl-5-iodocytosine
5-IC
5-Iodcytidin
5-Jod-cytidin
MFCD00056070

Biological Activity

[Description]:

5-Iodo-cytidine (5-Iodo-D-cytidine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
2.52 g/cm3

[ Boiling Point ]:
565.5ºCat 760 mmHg

[ Molecular Formula ]:
C₉H₁₂IN₃O₅

[ Molecular Weight ]:
369.11

[ Flash Point ]:
295.8ºC

[ Exact Mass ]:
368.98200

[ PSA ]:
130.83000

[ Appearance of Characters ]:
Crystalline or Powder | White to Off-white

[ Vapour Pressure ]:
3.85E-15mmHg at 25°C

[ Index of Refraction ]:
1.85

[ Storage condition ]:
-20°C

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
24/25

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%