TC NTR1 17

Names

[ Name ]:
TC NTR1 17

[Synonym ]:
L-Leucine, N-[[1-(7-chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-
N-{[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl}-L-leucine
ML 301 analog
N-[[1-(7-Chloro-4-quinolinyl)-5-(2,6-dimethoxyphenyl)-1H-pyrazol-3-yl]carbonyl]-L-leucine

Biological Activity

[Description]:

TC NTR1 17 is a selective NTSR1 agonist. TC NTR1 17 decreases the firing rate of the neurons[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Neurological Disease

[References]

[1]. Tabarean IV. Neurotensin induces hypothermia by activating both neuronal neurotensin receptor 1 and astrocytic neurotensin receptor 2 in the median preoptic nucleus. Neuropharmacology. 2020 Jul;171:108069.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
714.4±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₇H₂₇ClN₄O₅

[ Molecular Weight ]:
522.98

[ Flash Point ]:
385.8±32.9 °C

[ Exact Mass ]:
522.166992

[ LogP ]:
3.75

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.636

Related Compounds

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