Phenylac-Gly-Lys-OH

Names

[ CAS No. ]:
113969-25-8

[ Name ]:
Phenylac-Gly-Lys-OH

[Synonym ]:
6-amino-2-[[2-[(2-phenylacetyl)amino]acetyl]amino]hexanoic acid

Biological Activity

[Description]:

(S)-6-Amino-2-(2-(2-phenylacetamido)acetamido)hexanoic acid is a lysine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₂₃N₃O₄

[ Molecular Weight ]:
321.37200

[ Exact Mass ]:
321.16900

[ PSA ]:
121.52000

[ LogP ]:
1.52580

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

3-hydroxykynurenine-mediated modification of human lens proteins: structure determination of a major modification using a monoclonal antibody.

J. Biol. Chem. 280 , 22154-22164, (2005)

Tryptophan can be oxidized in the eye lens by both enzymatic and non-enzymatic mechanisms. Oxidation products, such as kynurenines, react with proteins to form yellow-brown pigments and cause covalent...

Elucidation of a novel polypeptide cross-link involving 3-hydroxykynurenine.

Biochemistry 38 , 11455-11464, (1999)

3-Hydroxykynurenine, a metabolite of tryptophan, is a powerful antioxidant and neurotoxin. The neurotoxicity results from the oxidation of 3-hydroxykynurenine, and hydroxyl radicals, formed via H(2)O(...

Polypeptide modification and cross-linking by oxidized 3-hydroxykynurenine.

Biochemistry 39 , 16176-16184, (2000)

3-Hydroxykynurenine (3OHKyn) is present in the mammalian lens as a UV filter and is formed from kynurenine in the tryptophan metabolic pathway. 3OHKyn is a readily autoxidized o-aminophenol which bind...

Related Compounds

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