4-Hydroxybenzophenone
Names
[ CAS No. ]:
1137-42-4
[ Name ]:
4-Hydroxybenzophenone
[Synonym ]:
1-benzoyl-4-hydroxy-benzene
P-HYDROXYBENZOPHENONE
POB
4-Hydroxybenzophenone
P-BENZOYLPHENOL
(4-Hydroxyphenyl)(phenyl)methanone
4-Hydroxybenzophene
4-BENZOYLPHENOL
Methanone, (4-hydroxyphenyl)phenyl-
PARA-BENZOYLPHENOL
EINECS 214-507-1
4-hydroxy-benzophenon
para-hydroxy-benzophenone
HYDROXYBENZOPHENONE-4
benzoylphenol
4-HYDROXY-BENZOPHENONE
MFCD00002355
4'-HYDROXYBENZOPHENONE
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
367.3±25.0 °C at 760 mmHg
[ Melting Point ]:
132-135 °C(lit.)
[ Molecular Formula ]:
C13H10O2
[ Molecular Weight ]:
198.217
[ Flash Point ]:
156.7±15.8 °C
[ Exact Mass ]:
198.068085
[ PSA ]:
37.30000
[ LogP ]:
2.87
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.615
[ Storage condition ]:
Refrigerator
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- PC4959775
- CHEMICAL NAME :
- Methanone, (4-hydroxyphenyl)phenyl-
- CAS REGISTRY NUMBER :
- 1137-42-4
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C13-H10-O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 12086 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),25,1994
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 3724 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),25,1994
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1154 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- TOVEFN Toksikologicheskii Vestnik. (18-20 Vadkovskii per. Moscow, 101479, Russia) History Unknown Volume(issue)/page/year: (2),25,1994
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36/37-S24/25
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
2
[ RTECS ]:
PC4959775
[ HS Code ]:
2914501900
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914501900
[ Summary ]:
2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 1005 , 1-8, (2015)
This work reports on a novel method involving reverse-phased ultra-high performance liquid chromatography (UHPLC) plus a spectrophotometric photodiode array/fluorescence (FLR) detection system for det...
Atmospheric pressure gas chromatography-time-of-flight-mass spectrometry (APGC-ToF-MS) for the determination of regulated and emerging contaminants in aqueous samples after stir bar sorptive extraction (SBSE).Anal. Chim. Acta 851 , 1-13, (2014)
This work presents the development, optimization and validation of a multi-residue method for the simultaneous determination of 102 contaminants, including fragrances, UV filters, repellents, endocrin...
Determination of benzophenone-UV filters in human milk samples using ultrasound-assisted extraction and clean-up with dispersive sorbents followed by UHPLC-MS/MS analysis.Talanta 134 , 657-64, (2015)
A new sample preparation method for the determination of five benzophenone UV-filters in human breast milk has been developed. The procedure involves the lyophilization of the sample, and its subseque...