N6-Methyladenosine N1-oxide

Names

[ Name ]:
N6-Methyladenosine N1-oxide

[Synonym ]:
N6-methyladenosine N1-oxide
(2R,3S,4R,5R)-2-Hydroxymethyl-5-(6-methylamino-1-oxy-purin-9-yl)-tetrahydro-furan-3,4-diol

Biological Activity

[Description]:

N6-Methyladenosine N1-oxide is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₁H₁₅N₅O₅

[ Molecular Weight ]:
297.27

[ Exact Mass ]:
297.10700

[ PSA ]:
138.12000