DMPQ dihydrochloride

Names

[ Name ]:
DMPQ dihydrochloride

[Synonym ]:
MFCD02262123
Quinoline, 5,7-dimethoxy-3-(4-pyridinyl)-, hydrochloride (1:2)
5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
5,7-Dimethoxy-3-(pyridin-4-yl)quinoline dihydrochloride
DMPQ dihydrochloride
DMPQ (hydrochloride)

Biological Activity

[Description]:

DMPQ dihydrochloride is a potent and selective inhibitor of human platelet-derived growth factor receptor β (PDGFRβ) with an IC50 of 80 nM[1].

[Related Catalog]:

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> PDGFR

Research Areas >> Others

[References]

[1]. Dolle RE, et al. 5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase. J Med Chem. 1994 Aug 19;37(17):2627-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₆H₁₆Cl₂N₂O₂

[ Molecular Weight ]:
339.216

[ Exact Mass ]:
338.058868

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

Related Compounds

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