IGF-1R inhibitor-2

Names

[ CAS No. ]:
1116236-15-7

[ Name ]:
IGF-1R inhibitor-2

Biological Activity

[Description]:

IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R

[Target]

IGF-1R


[References]

[1]. Stanley Dawes Chamberlain, et al. IR receptor tyrosine kinase and ALK kinase for treating cancer. WO2009020990 A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C24H24FN7O2

[ Molecular Weight ]:
461.49

[ Storage condition ]:
-20°C

Related Compounds