1116236-15-7

1116236-15-7 structure

Name: IGF-1R inhibitor-2
Chemical Name: IGF-1R inhibitor-2
CAS Number: 1116236-15-7
Molecular Formula: C₂₄H₂₄FN₇O₂
Molecular Weight: 461.49
Catalog: Signaling Pathways Protein Tyrosine Kinase/RTK IGF-1R
Create Date: 2022-02-21 10:05:49
Modify Date: 2025-09-04 11:22:48
IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis[1].

Name	IGF-1R inhibitor-2

Description	IGF-1R inhibitor-2 (example 121) is an insulin-like growth factor-1 receptor (IGF-1R) inhibitor. Downregulation of IGF-1R can reverse the transformed phenotype of tumor cells and potentially render them susceptible to apoptosis[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> IGF-1R
Target	IGF-1R
References	[1]. Stanley Dawes Chamberlain, et al. IR receptor tyrosine kinase and ALK kinase for treating cancer. WO2009020990 A1.