XTT sodium

Names

[ Name ]:
XTT sodium

[Synonym ]:
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide sodium
MFCD00191206
2,3-bis((2-hydroxyethyl)thio)naphthoquinone
2,3-Bis(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide inner salt
2,3-bis(2-methoxy-4-nitro-5-sulfophenyl)-tetrazolium-5-carboxanilide sodium
2,3-bis-(2-hydroxy-ethylsulfanyl)-[1,4]naphthoquinone
2,3-Bis(2-hydroxyethylthio)-1,4-naphthalenedione
2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione
Sodium3,3'-[1-(phenylamino)carbonyl]-3,4-tetrazolium-bis(4-methoxy-6-nitro)benzenesulfonic acid
1,4-Naphthalenedione,2,3-bis[(2-hydroxyethyl)thio]
2,3-bis[(2-Hydroxyethyl)thio]-1,4-naphthoquinone

Biological Activity

[Description]:

XTT (sodium) is used to assess cell viability as a function of redox potential. Actively respiring cells convert the water-soluble XTT to a water-soluble, orange colored formazan product.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Zhao Q, Ernst JT, Hamilton AD, Debnath AK, Jiang S. XTT formazan widely used to detect cell viability inhibits HIV type 1 infection in vitro by targeting gp41. AIDS Res Hum Retroviruses. 2002;18(14):989-997.

Chemical & Physical Properties

[ Melting Point ]:
41678ºC

[ Molecular Formula ]:
C₂₂H₁₆N₇NaO₁₃S₂

[ Molecular Weight ]:
715.53400

[ Exact Mass ]:
715.02300

[ PSA ]:
305.17000

[ LogP ]:
3.37520

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
hot water: 2.5 mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
26-37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

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