<Suppliers Price>

BocNH-PEG6-CH2CH2NH2

Names

[ CAS No. ]:
1091627-77-8

[ Name ]:
BocNH-PEG6-CH2CH2NH2

[Synonym ]:
t-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosylcarbamate
22-AMINO-5,8,11,14,17,20-HEXAOXA-2-AZADOCOSANOIC ACID 1,1-DIMETHYLETHYL ESTER
Boc-NH-PEG6-CH2CH2NH2

Biological Activity

[Description]:

Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

[ Molecular Formula ]:
C19H40N2O8

[ Molecular Weight ]:
424.53000

[ Exact Mass ]:
424.27800

[ PSA ]:
123.22000

[ LogP ]:
1.47410

Related Compounds