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1091627-77-8

1091627-77-8 structure
1091627-77-8 structure
  • Name: BocNH-PEG6-CH2CH2NH2
  • Chemical Name: tert-butyl N-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
  • CAS Number: 1091627-77-8
  • Molecular Formula: C19H40N2O8
  • Molecular Weight: 424.53000
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2018-12-31 16:56:07
  • Modify Date: 2025-08-20 19:51:50
  • Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name tert-butyl N-[2-[2-[2-[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Synonyms t-butyl 20-amino-3,6,9,12,15,18-hexaoxaicosylcarbamate
22-AMINO-5,8,11,14,17,20-HEXAOXA-2-AZADOCOSANOIC ACID 1,1-DIMETHYLETHYL ESTER
Boc-NH-PEG6-CH2CH2NH2
Description Boc-NH-PEG6-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C19H40N2O8
Molecular Weight 424.53000
Exact Mass 424.27800
PSA 123.22000
LogP 1.47410
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