Dibenzyl diisopropylphosphoramidoite
Names
[ CAS No. ]:
108549-23-1
[ Name ]:
Dibenzyl diisopropylphosphoramidoite
[Synonym ]:
MFCD00191988
Dibenzyl diisopropylphosphoramidoite
Dibenzyl diisopropylphosphoramidite
Phosphoramidous acid, bis(1-methylethyl)-, bis(phenylmethyl) ester
Dibenzyloxy(diisopropylamino)phosphine
N-bis(phenylmethoxy)phosphanyl-N-propan-2-ylpropan-2-amine
Dibenzyl N,N-Diisopropylphosphoramidite
Phosphoramidous acid, N,N-bis(1-methylethyl)-, bis(phenylmethyl) ester
Biological Activity
[Description]:
[Related Catalog]:
[In Vitro]
Chemical & Physical Properties
[ Density]:
1.028 g/mL at 25 °C(lit.)
[ Boiling Point ]:
382.0±31.0 °C at 760 mmHg
[ Molecular Formula ]:
C20H28NO2P
[ Molecular Weight ]:
345.42
[ Flash Point ]:
184.8±24.8 °C
[ Exact Mass ]:
345.185760
[ PSA ]:
35.29000
[ LogP ]:
6.82
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.535(lit.)
[ Storage condition ]:
Store at 0°C
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2931900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Angew. Chem. Int. Ed. Engl. 53(1) , 199-204, (2014)
We report the synthesis of a GDP analogue, SML-8-73-1, and a prodrug derivative, SML-10-70-1, which are selective, direct-acting covalent inhibitors of the K-Ras G12C mutant relative to wild-type Ras....
Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody.Mol. Endocrinol. 14(1) , 52-65, (2000)
Human progesterone receptor (PR) is phosphorylated on multiple serine residues (at least seven sites) in a manner that involves distinct groups of sites coordinately regulated by hormone and different...
A new reaction for the direct conversion of 4-azido-4-deoxy-D-galactoside into a 4-deoxy-D-erythro-hexos-3-ulose.Org. Lett. 6 , 1365-1368, (2004)
[reaction: see text] A new one-step reaction has been developed for converting 4-azido-4-deoxy-d-galactoside into 4-deoxy-d-erythro-hexos-3-ulose by phosphoramidites and tetrazole. It is proposed that...