N-p-Tosylglycine

Names

[ Name ]:
N-p-Tosylglycine

[Synonym ]:
Glycine, N-[(4-methylphenyl)sulfonyl]-
N-[(4-Methylphenyl)sulfonyl]glycine
2-(4-Methylphenylsulfonamido)acetic acid
N-P-TOSYLGLYCINE
2-[(4-methylphenyl)sulfonylamino]acetic acid
N-(p-Toluenesulfonyl)glycine
N-Tosylglycine
MFCD00045898
tos-gly-oh

Biological Activity

[Description]:

N-p-Tosylglycine is a Glycine (HY-Y0966) derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
430.0±55.0 °C at 760 mmHg

[ Melting Point ]:
147-149 °C(lit.)

[ Molecular Formula ]:
C₉H₁₁NO₄S

[ Molecular Weight ]:
229.253

[ Flash Point ]:
213.9±31.5 °C

[ Exact Mass ]:
229.040878

[ PSA ]:
91.85000

[ LogP ]:
1.07

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.568

[ Storage condition ]:
2-8°C

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Facilitation of insulin release by N-p-tosylglycine.

Biochem. Pharmacol. 34(14) , 2495-9, (1985)

N-p-tosylglycine, which inhibits transglutaminase activity in islet homogenates, was found to cause a rapid and sustained facilitation of insulin release evoked by D-glucose, L-leucine or the associat...