2-Methylthiirane
Names
[ CAS No. ]:
1072-43-1
[ Name ]:
2-Methylthiirane
[Synonym ]:
Thiirane, 2-methyl-
Methylethylene Sulfide
MFCD00005160
2-Methylthiirane
EINECS 214-007-3
Propylene sulfide
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
75.9±8.0 °C at 760 mmHg
[ Molecular Formula ]:
C3H6S
[ Molecular Weight ]:
74.145
[ Flash Point ]:
10.0±0.0 °C
[ Exact Mass ]:
74.019020
[ PSA ]:
25.30000
[ LogP ]:
0.70
[ Vapour Pressure ]:
113.2±0.1 mmHg at 25°C
[ Index of Refraction ]:
1.520
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TZ2625000
- CHEMICAL NAME :
- Propane, 1,2-epithio-
- CAS REGISTRY NUMBER :
- 1072-43-1
- BEILSTEIN REFERENCE NO. :
- 0383559
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C3-H6-S
- MOLECULAR WEIGHT :
- 74.15
- WISWESSER LINE NOTATION :
- T3STJ B1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 254 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Lungs, Thorax, or Respiration - structural or functional change in trachea or bronchi Lungs, Thorax, or Respiration - respiratory depression
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 25,560,1964
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 660 ppm/6H
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - fibrosis, focal (pneumoconiosis) Lungs, Thorax, or Respiration - acute pulmonary edema Blood - hemorrhage
- REFERENCE :
- BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 6,509,1971
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 44 mg/kg
- TOXIC EFFECTS :
- Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 25,560,1964
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 400 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RAREAE Radiation Research. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1954- Volume(issue)/page/year: 7,13,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7180 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H225-H301-H315-H319-H332
[ Precautionary Statements ]:
P210-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
F: Flammable;Xn: Harmful;
[ Risk Phrases ]:
11-20/22-36/38
[ Safety Phrases ]:
S16-S26-S36
[ RIDADR ]:
UN 1992 3/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
TZ2625000
[ Packaging Group ]:
II
[ Hazard Class ]:
3.1
Synthetic Route
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