Cytidine, N-methyl-

Names

[ Name ]:
Cytidine, N-methyl-

[Synonym ]:
Cytidine,N-methyl
4-N-Methylcytidine
N4-Methyl-cytidin
N4-Methylcytidine

Biological Activity

[Description]:

N4-Methylcytidine (Nsc518744) is a cytidine nucleoside analog. Cytidine analogs have a mechanism of inhibiting DNA methyltransferases (such as Zebularine, HY-13420), and have potential anti-metabolic and anti-tumor activities[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Gowher H, et al. Mechanism of inhibition of DNA methyltransferases by cytidine analogs in cancer therapy. Cancer Biol Ther. 2004 Nov;3(11):1062-8.

Chemical & Physical Properties

[ Density]:
1.69g/cm3

[ Boiling Point ]:
504.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₅N₃O₅

[ Molecular Weight ]:
257.24

[ Flash Point ]:
258.7ºC

[ Exact Mass ]:
257.10100

[ PSA ]:
116.84000

[ Vapour Pressure ]:
2.82E-12mmHg at 25°C

[ Index of Refraction ]:
1.694

[ Storage condition ]:
2-8°C

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%