1-Piperidinepropanol

Names

[ CAS No. ]:
104-58-5

[ Name ]:
1-Piperidinepropanol

[Synonym ]:
3-Piperidino-1-propanol
3-piperidin-1-ylpropan-1-ol
3-(1-Piperidino)propanol
Piperidine-1-propanol
1-Propanol, 3-piperidino-
1-Piperidinepropanol
3-(piperidin-1-yl)propan-1-ol
3-(1-Piperidinyl)-1-propanol
MFCD00023781
EINECS 203-216-5
3-piperidino-propan-1-ol
3-Piperidinopropanol
1-Propanol,3-piperidino

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
237.9±23.0 °C at 760 mmHg

[ Molecular Formula ]:
C₈H₁₇NO

[ Molecular Weight ]:
143.227

[ Flash Point ]:
105.6±21.3 °C

[ Exact Mass ]:
143.131012

[ PSA ]:
23.47000

[ LogP ]:
0.46

[ Vapour Pressure ]:
0.0±1.0 mmHg at 25°C

[ Index of Refraction ]:
1.477

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TN2414500

CHEMICAL NAME :: 1-Piperidinepropanol

CAS REGISTRY NUMBER :: 104-58-5

BEILSTEIN REFERENCE NO. :: 0001275

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H17-N-O

MOLECULAR WEIGHT :: 143.26

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 58 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHARAT Pharmazie. (VEB Verlag Volk und Gesundheit, Neue Gruenstr. 18, Berlin DDR-1020, Ger. Dem. Rep.) V.1- 1946- Volume(issue)/page/year: 14,201,1959 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7918 No. of Facilities: 4 (estimated) No. of Industries: 1 No. of Occupations: 16 No. of Employees: 1440 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
TN2414500

[ HS Code ]:
2933399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Synthesis and evaluation of N-alkyl-S-[3-(piperidin-1-yl)propyl]isothioureas: High affinity and human/rat species-selective histamine H3 receptor antagonists

Bioorg. Med. Chem. Lett. 23(23) , 6415-20, (2013)

OUP-186: histamine H3R antagonist inactive in rats, but especially potent in humans.