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4'-Methylsulphonylacetophenone

Names

[ CAS No. ]:
10297-73-1

[ Name ]:
4'-Methylsulphonylacetophenone

[Synonym ]:
4-Methylsulphonylacetophenone
MFCD00025072
EINECS 233-672-0
4-(Methylsulfonyl)Acetophenone
4-Acetophenone methyl sulfone
1-(4-(Methylsulphonyl)phenyl)ethan-1-one
1-[4-(methylsulfonyl)phenyl]ethan-1-one
1-[4-(Methylsulfonyl)phenyl]ethanone
Ethanone, 1-(4-methylsulfonylphenyl)-
Ethanone, 1-[4-(methylsulfonyl)phenyl]-
1-(4-methylsulfonylphenyl)ethanone
Etoricoxib Impurity 19
4'-Methylsulphonylacetophenone

Biological Activity

[Description]:

p-Methylsulfonylacetophenone is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

[In Vitro]

依托考昔的杂质

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
385.4±34.0 °C at 760 mmHg

[ Melting Point ]:
126-129 °C(lit.)

[ Molecular Formula ]:
C9H10O3S

[ Molecular Weight ]:
198.24

[ Flash Point ]:
242.0±18.3 °C

[ Exact Mass ]:
198.035065

[ PSA ]:
59.59000

[ LogP ]:
0.40

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.521

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2914700090

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents.

J. Natl. Cancer Inst. 94(23) , 1745-57, (2002)

The cyclooxygenase-2 (COX-2) inhibitor celecoxib is thought to act as a chemopreventive agent by sensitizing cancer cells to apoptotic signals. Other COX-2 inhibitors, such as rofecoxib, are two order...

Synthesis and biological evaluation of N-substituted-3,5-diphenyl-2-pyrazoline derivatives as cyclooxygenase (COX-2) inhibitors

Eur. J. Med. Chem. 45 , 6135-8, (2010)

Eighteen new 1-N-substituted-3,5-diphenyl-2-pyrazoline derivatives have been synthesized and cyclooxygenase (COX-1 and COX-2) inhibitory activities have been evaluated. The results of these biological...

New Antibacterial Agents. II. An Alternate Synthesis of DL-threo-2-Dichloro-acetamido-1-(4-methylsulfonylphenyl)-1, 3-propanediol1. Suter CM, et al.

J. Am. Chem. Soc. 75(17) , 4330-4333, (1953)


More Articles


Related Compounds

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