2-Cyanoethyltetraisopropylphosphorodiamidite
Names
[ CAS No. ]:
102691-36-1
[ Name ]:
2-Cyanoethyltetraisopropylphosphorodiamidite
[Synonym ]:
3-bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite
2-cyanoethyl N,N,N',N'-tetrapropan-2-ylphosphorodiamidoite
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidoite
2-Cyanoethyl N,N,N,N-tetraisopropylphosphordiamidite
2-Cyanoethyl N,N,N′,N′-tetraisopropylphosphordiamidite
Phosphorodiamidous acid, N,N,N',N'-tetrakis(1-methylethyl)-, 2-cyanoethyl ester
Phosphorodiamidous acid, tetrakis(1-methylethyl)-, 2-cyanoethyl ester
Bis(diisopropylamino)(2-cyanoethoxy)phosphine
MFCD00012213
2-Cyanoethyl N,N,N',N'-tetraisopropyldiamidophosphite
2-Cyanoethyl N,N,N',N'-tetraisopropylphosphordiamidite
3-((Bis(diisopropylamino)phosphino)oxy)propanenitrile
2-Cyanoethyltetraisopropylphosphorodiamidite
2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphorodiamidite
Chemical & Physical Properties
[ Density]:
0.949 g/mL at 25 °C(lit.)
[ Boiling Point ]:
298.1±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C15H32N3OP
[ Molecular Weight ]:
301.408
[ Flash Point ]:
177.9±28.4 °C
[ Exact Mass ]:
301.228302
[ PSA ]:
53.09000
[ LogP ]:
4.00
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
n20/D 1.470(lit.)
[ Storage condition ]:
2-8°C
[ Stability ]:
Explodes When Heated
MSDS
Safety Information
[ Symbol ]:
GHS02, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H315-H317-H319-H334
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P342 + P311
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R5;R36/37/38
[ Safety Phrases ]:
S3-S26-S36
[ RIDADR ]:
UN 1993 3/PG 3
[ WGK Germany ]:
3
[ Packaging Group ]:
I
[ Hazard Class ]:
8
[ HS Code ]:
2926909090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2926909090
[ Summary ]:
HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
Nucleic Acids Res. 35(5) , 1441-51, (2007)
The synthesis of oligonucleotides containing 2'-deoxy-2'-fluoro-4'-thioarabinonucleotides is described. 2'-Deoxy-2'-fluoro-5-methyl-4'-thioarabinouridine (4'S-FMAU) was incorporated into 18-mer antise...
DNA adducts of acrolein: site-specific synthesis of an oligodeoxynucleotide containing 6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one, an acrolein adduct of guanine.Chem. Res. Toxicol. 15(5) , 607-13, (2002)
3-(2-Deoxy-beta-D-erythro-pentofuranosyl)-6-hydroxy-5,6,7,8-tetrahydropyrimido[1,2-a]purin-10(3H)-one is formed in low yield by the reaction of acrolein with 2'-deoxyguanosine. The nucleoside and an o...
Synthesis and fluorescence studies of multiple labeled oligonucleotides containing dansyl fluorophore covalently attached at 2'-terminus of cytidine via carbamate linkage.Bioconjug. Chem. 15 , 638-646, (2004)
Synthesis of modified oligonucleotides in which the specific cytidine nucleoside analogues linked at 2'-OH position via a carbamate bond with an amino ethyl derivative of dansyl fluorophore is reporte...