Biomaterials 1984-05-01

Preparation of an asymmetric semipermeable membrane with anticoagulant activity.

G Crassous, M Jozefowicz, J Sledz

Index: Biomaterials 5(3) , 153-6, (1984)

Full Text: HTML

Abstract

In this paper we report the preparation of a new asymmetric semipermeable styrene-isoprene-styrene block-copolymer membrane. Its modification by addition of gaseous N-chlorosulphonylisocyanate alters neither its permselectivity nor its water permeability rate. This modified membrane possesses an antithrombic activity which depends on antithrombin III. The actual active surface in contact with proteins is very large because the whole macroporous underlayer is modified and accessible to the proteins.

Related Compounds

Related Articles:

Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.

2013-06-01

[Bioorg. Med. Chem. 21(11) , 2925-31, (2013)]

Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases.

1993-06-15

[J. Biol. Chem. 268(17) , 12933-8, (1993)]

Kinetic studies on the reaction of chlorosulfonyl isocyanate with monofluoroalkenes: experimental evidence for both stepwise and concerted mechanisms and a pre-equilibrium complex on the reaction pathway.

2013-01-18

[J. Org. Chem. 78(2) , 246-52, (2013)]

Synthesis of (2R,5S)-dihydroxymethyl-(3R,4R)-dihydroxypyrrolidine (DGDP) via stereoselective amination using chlorosulfonyl isocyanate.

2007-08-13

[Carbohydr. Res. 342(11) , 1502-9, (2007)]

Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 17. Structure-activity relationships of several series of compounds derived from N-chlorosulfonyl isocyanate.

1996-03-15

[J. Med. Chem. 39(6) , 1243-52, (1996)]

More Articles...