Chlorosulfonylisocyanate

[ Density]:
1.8±0.1 g/cm3

[ Boiling Point ]:
107.0±9.0 °C at 760 mmHg

[ Melting Point ]:
−44 °C(lit.)

[ Molecular Formula ]:
CClNO₃S

[ Molecular Weight ]:
141.534

[ Flash Point ]:
18.5±18.7 °C

[ Exact Mass ]:
140.928741

[ PSA ]:
71.95000

[ LogP ]:
1.23

[ Vapour Pressure ]:
32.2±0.2 mmHg at 25°C

[ Index of Refraction ]:
1.550

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
reacts violently exothermic

Click to get detail MSDS

[ Symbol ]:

GHS05, GHS07, GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H314-H334

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
C:Corrosive

[ Risk Phrases ]:
R14;R20/22;R34;R42

[ Safety Phrases ]:
S23-S26-S30-S36/37/39-S45

[ RIDADR ]:
UN 3265 8/PG 2

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2929109000

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synthesis and carbonic anhydrase inhibitory properties of sulfamides structurally related to dopamine.

Bioorg. Med. Chem. 21(11) , 2925-31, (2013)

A series of novel sulfamides incorporating the dopamine scaffold were synthesized. Reaction of amines and tert-butyl-alcohol/benzyl alcohol in the presence of chlorosulfonyl isocyanate (CSI) afforded ...

Synthesis and characterization of a new class of inhibitors of membrane-associated UDP-glycosyltransferases.

J. Biol. Chem. 268(17) , 12933-8, (1993)

A new class of compounds designed to inhibit membrane-associated glycosyltransferases were synthesized and their biological activities were characterized in liver microsomes and human lymphoma cell li...

Kinetic studies on the reaction of chlorosulfonyl isocyanate with monofluoroalkenes: experimental evidence for both stepwise and concerted mechanisms and a pre-equilibrium complex on the reaction pathway.

J. Org. Chem. 78(2) , 246-52, (2013)

Chlorosulfonyl isocyanate (CSI) is reported to react with hydrocarbon alkenes by a stepwise dipolar pathway to give N-chlorosulfonyl-β-lactams that are readily reduced to β-lactams. Substitution of a ...

More Articles