Tetrahedron letters

2, 4-Dinitrobenzenesulfonamides: A simple and practical method for the preparation of a variety of secondary amines and diamines

T Fukuyama, M Cheung, CK Jow, Y Hidai, T Kan

Index: Fukuyama, Tohru; Cheung, Mui; Jow, Chung-Kuang; Hidai, Yuko; Kan, Toshiyuki Tetrahedron Letters, 1997 , vol. 38, # 33 p. 5831 - 5834

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Citation Number: 307

Abstract

2, 4-Dinitrobenzenesulfonamides, readily prepared from primary amines and 2, 4- dinitrobenzenesulfonyl chloride, can be alkylated by the Mitsunobu reaction or by the conventional methods to give N, N-disubstituted sulfonamides in excellent yields. Since 2, 4- dinitrobenzenesulfonamides can be removed without deprotecting 2- nitrobenzenesulfonamides, a wide variety of diamines could be prepared by the combined ...

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